Vanderbilt School of Medicine | Vanderbilt University | Vanderbilt Medical Center



Welcome to the Bordenstein laboratory!

We endeavor to understand the principles that shape interactions between hosts, microbes, and viruses and the major consequences and applications of these interactions. Four key questions that drive basic and translational outcomes are:

  • How did life go from one to many millions of species today? How is the microbiome involved in the processes of speciation? Info | News | Pubs
  • How do viral genomes evolve and function in intracellular bacteria? Info | News | Pubs
  • Will bioprospecting Archaea fuel discovery of new antibiotics? Publication | News
  • What is the relative importance of vertical and environmental transmission of the microbiome in animals? Info | News | Pubs


News & Events

April 2016 - Getting the Hologenome Concept Right: An Eco-Evolutionary Framework for Hosts and Their Microbiomes. Collaboration with 15 biologists and philosophers. mSystems

April 2016 - Airway bacteria drive a progressive COPD-like phenotype in mice with polymeric immunoglobulin receptor deficiency. Nature Communications Collaboration with Blackwell Lab et al.

April 2016 - Speciation by Symbiosis: The Microbiome and Behavior. New from Dylan Shropshire in mBio Link

March 2016 - "Wolbachia pipientis should not be split into multiple species". Link Collaboration with Amelia Lindsey, Irene Newton, and Jason Rasgon

December 2015 - Discovery of lateral gene transfers from two endosymbionts (Wolbachia) into the same animal genome. New from graduate student Lisa Funkhouser-Jones in PeerJ (open access, link, graphical abstract)

September 2015 - New perspective and podcast on host genes, community ecology, and heritability of the microbiome in Science (Link and pdf) | By graduate student Teddy Van Opstal