Vanderbilt

Vanderbilt School of Medicine | Vanderbilt University | Vanderbilt Medical Center

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Welcome to the Bordenstein laboratory

We endeavor to understand the principles that shape interactions between hosts, microbes, and viruses and the major consequences and applications of these interactions. Four key questions that drive basic and translational outcomes are:

  • How did life go from one to many millions of species today? How is the microbiome involved in the processes of speciation? Info | News | Pubs
  • How do viral genomes evolve and function in intracellular bacteria? Info | News | Pubs
  • Will bioprospecting Archaea fuel discovery of new antibiotics? Publication | News
  • What is the relative importance of vertical and environmental transmission of the microbiome in animals? Info | News | Pubs

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News & Events

July 2016 - Fecal transplants: What is being transferred? PLOS Biology (open access)

June 2016 - Physiological and microbial adjustments to diet quality permit facultative herbivory in an omnivorous lizard. New from Kevin Kohl et al. Journal of Experimental Biology

May 2016 - Comparative genomics of two closely related Wolbachia with different host effects. Collaboration with Irene Newton et al. Genome Biology and Evolution (open access)

April 2016 - Seth joins colleagues to briefly discuss Wolbachia-based strategies of mosquito control. Collaboration with Stephen Dobson and Robert Rose. Science

April 2016 - Getting the Hologenome Concept Right: An Eco-Evolutionary Framework for Hosts and Their Microbiomes. Collaboration with 15 biologists and philosophers. mSystems (open access)

April 2016 - Airway bacteria drive a progressive COPD-like phenotype in mice with polymeric immunoglobulin receptor deficiency. Nature Communications Collaboration with Blackwell Lab et al. (open access)

April 2016 - Speciation by Symbiosis: The Microbiome and Behavior. New from Dylan Shropshire in mBio Link (open access)